About the Journal

Annals of Real-World Data & Evidence (ARWDE) /pronounced RWD/ is an international, multidisciplinary journal publishing original research, methodological frameworks, data source profiles, application presentations, and protocols in the field of non-interventional studies. The journal addresses the critical need for methodological rigor in the use of real-world data (RWD) for real-world evidence (RWE) generation for clinical, commercial, regulatory and health-technology assessment decision-making. Key areas of focus include data provenance and quality appraisal, data science methods, target trial emulation, bias mitigation, and the application of artificial intelligence in evidence generation. By bridging the gap between informatics and clinical outcomes, ARWDE provides a specialized platform for the dissemination of evidence that meets the evolving requirements of global health authorities and payers.

 
Annals of Real-World Data & Evidence
Where Data Meets Decisions
 
Welcome to the Annals of Real-World Data & Evidence (ARWDE)—the premier open-access journal dedicated to transforming real-world data into credible, actionable evidence for clinicians, regulators, and health decision-makers worldwide.
 
Published by the Elixir Institute, ARWDE bridges classical scholarly rigor with modern data-science excellence. We provide a trusted forum for:
  • Data custodians showcasing infrastructure transparency
  • Methodologists advancing causal inference and AI validation
  • Regulators & HTA bodies accessing auditable evidence frameworks
  • Industry leaders demonstrating real-world value generation
All articles undergo rigorous double-blind peer review and publish Gold Open Access under CC BY 4.0—ensuring global reach while authors retain full copyright.
 
Elevate your evidence. Shape the future of healthcare decisions.